After a tight first quarter, Philadelphia opened up an eight-point lead at halftime. Boston closed the gap to two heading into the fourth quarter, but the Sixers pulled away in the final frame.
Wright scored his 20 points in 25 strong minutes off the bench, going 7-of-11 from the field and 2-of-4 from three-point land. Fellow bench mate Nick Young also delivered, scoring 15 points and pulling down six rebounds.
Boston got strong performances from Rajon Rondo and Jeff Green, with both guys notching double-doubles. Rookie big man Jared Sullinger had a nice performance off the bench, scoring 11 points and grabbing six boards in 28 minutes.
Philadelphia improved to 5-1 on the preseason, with just one game left against the New York Knicks before the real games start.
Boston finished up their preseason slate with a 5-3 record.