Philadelphia (3-1) survived two potential game-winning field goal attempts by New York Giants kicker Lawrence Tynes to earn the 19-17 win in Week 4. Quarterback Michael Vick, with his play being questioned before the contest, turned in a solid performance, completing 19-of-30 passes for 241 yards, a touchdown and no interceptions. He also ran six times for 49 yards.
Meanwhile, the Steelers (1-2) are coming off their bye week hoping for the return of defensive stalwarts Troy Polamalu and James Harrison as well as running back Rashard Mendenhall, who will hope to aid Pittsburgh's rushing offense, which, with an average of 65 yards per game, ranks 31st in the league.
The Steelers, playing at home, are favored by 3 points, according to OddsShark, while the over/under stands at 43.
Game time is set for 1 p.m. ET at Heinz Field, and the contest will be televised on Fox.