Cliff Lee went 10 sensational innings for Philadelphia, allowing seven hits and striking out seven batters. His efforts were ultimately in vein, however, as an 11th inning walk off single from Melky Cabrera pushed the Giants past the Phillies, and Lee was left with a no decision.
Matt Cain, who San Francisco made the richest right hander in baseball earlier this spring, threw nine scoreless frames of his own, allowing just two hits and one walk.
The Phillies struggles at the plate continued, and they are now 28th overall in the MLB in runs scored.
Philadelphia will head south on Thursday to begin a series with the San Diego Padres.