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French Open Results: John Isner Loses Marathon, Rafael Nadal Advances Easily

The 2012 French Open continued Thursday without many surprises. The biggest upset occurred when No. 10 American John Isner fell to Paul-Henri Mathieu, 6-7 (2), 6-4, 6-4, 3-6, 18-16, in a match that lasted five hours and 41 minutes. The match was the second longest in the history of the Open. Of course, the length of the match didn't come close to Isner's 11-hour, five-minute match against Nicolas Mahut during Wimbledon in 2010.

No. 2 Rafael Nadal and No. 4 Andy Murray both advanced, though Murray struggled somewhat. The Scotsman got a jolt in the first set against Jarkko Nieminen, losing 1-6 before winning three straight sets. Nadal utterly dominated Denis Istomin, winning 6-2, 6-2, 6-0, on his drive for an Open-era record seven French Open titles.

On the women's side of the draw, No. 4 Petra Kvitova, No. 7 Na Li and No. 9 Caroline Wozniacki all won easily in straight sets. Virginie Razzano, who knocked Serena Williams off in the opening round of the tournament, wasn't so lucky against Arantxa Rus of the Netherlands. She put up an impressive fight, however, before ultimately falling 3-6, 6-7 (10).

Due to the drawn out battle between Isner and Mathieu, the evening match between No. 2 Maria Sharapova and Ayumi Morita was postponed until Friday.

For full French Open results from SI.com, click here.

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