Lotulelei's stock had fallen in recent times as mystery surrounded a heart condition that was discovered in the hulking prospect. However, doctors have cleared the youngster, and he has once again found himself in the top five of mock drafts.
The 23-year-old racked up five sacks and 42 tackles last season in the Pac-12.
Philadelphia needs a big body on the interior of its defensive line after losing Cullen Jenkins. Lotulelei is also a great fit for the Eagles because he can play in any formation as either a nose tackle or a regular defensive tackle in a 4-3 scheme.
The Eagles would also have to consider Dee Milliner in this position as a team with needs in the secondary. Milliner is the best cornerback available and coming off another championship run with the Alabama Crimson Tide.